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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA3
All Species:
45.15
Human Site:
T485
Identified Species:
62.08
UniProt:
P30101
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30101
NP_005304.3
505
56782
T485
S
Y
L
Q
R
E
A
T
N
P
P
V
I
Q
E
Chimpanzee
Pan troglodytes
XP_001159528
485
54945
T465
S
Y
L
Q
R
E
A
T
N
P
P
V
I
Q
E
Rhesus Macaque
Macaca mulatta
XP_001108948
480
54081
T460
S
Y
L
Q
R
E
A
T
N
P
P
V
I
Q
E
Dog
Lupus familis
XP_535453
687
75990
T667
S
Y
L
Q
R
E
A
T
N
P
P
V
I
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P27773
505
56660
T485
S
Y
L
Q
R
E
A
T
N
P
P
I
I
Q
E
Rat
Rattus norvegicus
P11598
505
56605
T485
S
Y
L
Q
R
E
A
T
N
P
P
I
I
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517928
483
54617
T462
S
Y
L
Q
R
E
A
T
N
P
P
V
I
Q
E
Chicken
Gallus gallus
Q8JG64
505
56163
T483
S
Y
L
K
R
E
A
T
S
T
P
V
L
Q
E
Frog
Xenopus laevis
NP_001080051
502
56103
T482
S
Y
L
K
K
E
A
T
N
P
P
V
V
K
E
Zebra Danio
Brachydanio rerio
NP_998070
488
54656
T476
T
Y
L
K
K
E
A
T
N
P
L
I
L
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A476
L
D
A
N
G
E
V
A
D
S
E
P
V
E
E
Honey Bee
Apis mellifera
XP_623282
490
55838
T470
K
Y
I
A
K
H
A
T
N
E
L
K
G
F
D
Nematode Worm
Caenorhab. elegans
P34329
618
69779
V609
K
F
M
T
K
H
G
V
K
S
F
Q
K
K
D
Sea Urchin
Strong. purpuratus
XP_782981
472
51996
T460
K
F
I
K
K
E
A
T
S
K
P
V
N
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
A487
I
K
K
S
K
E
T
A
A
P
H
H
H
H
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
K481
F
V
E
K
N
S
E
K
K
P
T
S
H
G
E
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
H485
D
F
I
K
E
N
G
H
F
D
V
D
G
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
94.4
70.8
N.A.
93
92.2
N.A.
84.7
80.9
74.6
60
N.A.
32.6
49.5
36.7
50.5
Protein Similarity:
100
92.6
94.8
72.1
N.A.
97
96.2
N.A.
90.3
90.8
88.3
77.2
N.A.
53.4
63.7
50.4
65.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
73.3
73.3
46.6
N.A.
13.3
26.6
0
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
86.6
N.A.
33.3
46.6
33.3
66.6
Percent
Protein Identity:
N.A.
34.3
N.A.
35.6
26.8
N.A.
Protein Similarity:
N.A.
51
N.A.
54.9
48.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
6
0
0
71
12
6
0
0
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
0
0
0
0
0
0
6
6
0
6
0
6
18
% D
% Glu:
0
0
6
0
6
77
6
0
0
6
6
0
0
6
65
% E
% Phe:
6
18
0
0
0
0
0
0
6
0
6
0
0
6
0
% F
% Gly:
0
0
0
0
6
0
12
0
0
0
0
0
12
6
6
% G
% His:
0
0
0
0
0
12
0
6
0
0
6
6
12
6
6
% H
% Ile:
6
0
18
0
0
0
0
0
0
0
0
18
42
0
0
% I
% Lys:
18
6
6
36
36
0
0
6
12
6
0
6
6
18
0
% K
% Leu:
6
0
59
0
0
0
0
0
0
0
12
0
12
0
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
6
6
0
0
59
0
0
0
6
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
65
59
6
0
0
0
% P
% Gln:
0
0
0
42
0
0
0
0
0
0
0
6
0
48
0
% Q
% Arg:
0
0
0
0
48
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
53
0
0
6
0
6
0
0
12
12
0
6
0
0
0
% S
% Thr:
6
0
0
6
0
0
6
71
0
6
6
0
0
6
0
% T
% Val:
0
6
0
0
0
0
6
6
0
0
6
48
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
65
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _